Vitamin B1 and B6 in the malaria parasite: requisite or dispensable?

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Vitamin B1 and B6 in the malaria parasite: requisite or dispensable?

Vitamins are essential compounds mainly involved in acting as enzyme co-factors or in response to oxidative stress. In the last two years it became apparent that apicomplexan parasites are able to generate B vitamers such as vitamin B1 and B6 de novo. The biosynthesis pathways responsible for vitamin generation are considered as drug targets, since both provide a high degree of selectivity due ...

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ژورنال

عنوان ژورنال: Brazilian Journal of Medical and Biological Research

سال: 2008

ISSN: 1414-431X,0100-879X

DOI: 10.1590/s0100-879x2008005000006